Lead: University of Birmingham

The objective of work package 2 (WP2) is to undertake a very focused set of experiments, designed purposefully to fill gaps identified in the existing large datasets that would prevent the in silico models from performing at optimum levels, and thus reduce the predictive power of the overall IATA. To facilitate the purposeful design of the experimental plan, WP2 will work with each of WPs 3-5 to support their analysis of the available datasets, and with work package 6 (WP6) to map the nanomaterials fingerprints and transformations data needed, and the input and output formats from each model. Based on this analysis, and the information needs identified, a design of experiments will be implemented to minimise the number of experiments needed. This will also be utilised to develop guidance for users of the final IATA on how best to generate the input data needed to run the IATA (in collaboration with WP6, also led by UoB).